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Irritant Dermatitis & Shaving Rashes: Causes, Treatment, and Recovery

The burning sensation started at your fingertips, spreading across your palms despite every moisturizer you've tried. Research confirms that irritant contact dermatitis accounts for approximately 80% of occupational contact dermatitis cases[1], with one study during the COVID-19 pandemic finding that 52.8% of healthcare workers reported signs of hand eczema[2]. Yet most sufferers never identify the true cause, cycling through ineffective treatments while their skin barrier continues to deteriorate.

Your journey to find relief has likely been a frustrating one. You've probably tried prescription creams, over-the-counter remedies, and maybe even natural oils, only for the irritation to return. This is an incredibly common experience. Research shows that only 28% of healthcare workers see a full recovery six months after diagnosis[3], and up to 67.7% of patients report emotional stress from the constant discomfort[4]. You are not just dealing with irritated skin; you're dealing with the daily impact on your work and life.

But what if the problem isn't the treatments, but how we're thinking about the condition itself?

If you searched for "shaving rash," you're in the right place. Shaving rash is a common form of irritant contact dermatitis caused by friction and product exposure. You can jump to Shaving and Friction for quick tips.

This article presents evidence-based information about irritant contact dermatitis, affecting millions worldwide with an incidence ranging from 0.6 to 6.7 per 10,000 full-time workers annually[5]. We'll examine the critical differences between irritant and allergic reactions, explore why certain skin types are more vulnerable, and discuss treatment approaches proven to improve outcomes by up to 63%[6]. You'll also learn about how dermatitis can spread and strategies for preventing progression. Our goal is to provide clear, scientifically accurate information that helps you understand your condition and make informed treatment decisions.

Recent research from leading dermatology centers demonstrates that combining barrier repair therapies with irritant avoidance achieves up to 63% improvement rates in previously treatment-resistant cases[6]. These findings offer renewed hope for those struggling with chronic irritant dermatitis.

Key Takeaways

  • 90-95% of occupational skin diseases are contact dermatitis - with irritant type being most common[15]
  • Direct skin damage, not allergy - irritant dermatitis occurs without immune sensitization
  • Wet work increases risk 3-fold - frequent hand washing and glove use are major triggers[20]
  • Recovery takes 2-4 weeks minimum - with proper treatment and irritant avoidance
  • Barrier repair is essential - moisturizers and protective measures prevent recurrence

What is Irritant Dermatitis?

Irritant dermatitis is a non-allergic skin inflammation caused by direct damage to your skin barrier from water, soaps, chemicals, friction, or heat. It can appear after a single strong exposure or develop slowly with repeated contact. Anyone can be affected with enough exposure, and it improves with irritant avoidance and barrier repair.

Irritant contact dermatitis (ICD) is a non-allergic skin reaction caused by direct damage to the skin's protective barrier. It is not an allergy but a direct injury from a substance, affecting anyone with sufficient exposure. It can appear as a rapid reaction to a strong irritant or develop slowly over time from repeated contact with milder ones[7].

The condition results from direct cytotoxic effects on skin cells. When irritants contact your skin, they physically or chemically damage the stratum corneum (outer layer), disrupting the delicate balance of lipids, proteins, and natural moisturizing factors that maintain barrier function[7]. This disruption triggers an inflammatory cascade involving pro-inflammatory cytokines and chemokines, leading to the characteristic symptoms of dermatitis[7].

Clinical Insight: Research shows that skin pH increases from its normal acidic range (4.1-5.8) during irritant exposure, further compromising barrier function and creating conditions favorable for secondary infections[8].

Types of Irritant Dermatitis

Irritant dermatitis isn't just one condition; it shows up in a few different ways depending on the irritant and the exposure time. Understanding which type you're dealing with is the key to finding the right solution and knowing how long healing will take.

Acute Irritant Dermatitis

This is the fast-acting type that develops rapidly after a single exposure to a strong irritant. Think of spilling a harsh cleaning chemical. Common triggers include concentrated acids, alkalis, or solvents that cause immediate skin damage[7]. Symptoms appear within minutes to hours and include:

  • Immediate burning or stinging sensation
  • Rapid onset of redness and swelling
  • Possible blistering in severe cases

Recovery typically occurs within 2-4 weeks with proper treatment and complete irritant avoidance[9]. However, severe cases with blistering may take longer to heal completely.

Chronic Irritant Dermatitis

This is the slow, creeping type of dermatitis that builds up over time from repeated exposure to milder irritants. It's the most common form found in the workplace, especially for healthcare workers, hairdressers, and food handlers who frequently have wet hands[10]. Chronic ICD accounts for the majority of occupational dermatitis cases, with studies showing prevalence rates of 38.2% among hairdressers[11].

Symptoms develop slowly over weeks to months:

  • Persistent dryness and scaling
  • Skin thickening (lichenification)
  • Painful fissures and cracks
  • Hyperpigmentation in chronic cases

Cumulative Irritant Dermatitis

The most insidious form, cumulative irritant dermatitis results from repeated, low-level damage that eventually overwhelms your skin's ability to repair itself[7]. Each exposure (like washing your hands one more time) may seem harmless, but the cumulative effect is what finally leads to a visible and painful rash.

50%

of hand dermatitis cases are caused by irritant contact dermatitis[12]

But what exactly is causing all this damage? The answer is often hiding in plain sight.

Common Causes and Triggers of Irritant Dermatitis

Identifying your specific irritants is the most critical step for successful management. Research shows that irritants fall into several common categories, and you are likely exposed to more than one every day[1].

Wet Work and Water

Paradoxically, water itself is a significant irritant. Frequent hand washing, especially with hot water, disrupts the skin's lipid barrier. Studies show that wet work exposure is a significant risk factor for occupational dermatitis[10]. Healthcare workers who wash hands more than 20 times per shift show significantly higher rates of irritant dermatitis[13].

Chemical Irritants

Common chemical irritants encountered daily include:

  • Soaps and detergents: Strip natural oils from skin
  • Solvents: Alcohol, acetone dissolve protective lipids
  • Acids and alkalis: Directly damage proteins in skin cells
  • Preservatives: Formaldehyde, methylisothiazolinone cause cumulative damage

Physical Irritants

Physical factors often overlooked include:

  • Friction from tools, clothing, or shaving
  • Low humidity environments
  • Temperature extremes
  • Occlusion from gloves or protective equipment

Shaving and Friction (Shaving Rash)

Shaving can trigger irritant dermatitis through repeated friction and microtrauma to the stratum corneum. Common contributors include:

  • Using dull blades that increase pressure and scraping
  • Dry shaving without adequate lubrication
  • Harsh foams or aftershaves with alcohol or strong fragrances
  • Tight collars or mask wear immediately after shaving (heat and occlusion)

Learn how to recognize and prevent shaving rash in our dedicated guide.

Now, this is a very important point. Many people think they have an allergy when they actually have an irritation. Let's clear up the confusion.

Irritant vs Allergic Contact Dermatitis: Critical Differences

Distinguishing between irritant and allergic contact dermatitis is essential, because the long-term management is different. While the rashes can look identical, their root causes are worlds apart[14].

Comparison of Irritant vs Allergic Contact Dermatitis
Factor Irritant Contact Dermatitis Allergic Contact Dermatitis
Mechanism Direct skin damage Type IV immune response
First exposure Can occur immediately Requires sensitization period
Affected population Anyone with sufficient exposure Only sensitized individuals (10-15%)[15]
Onset Minutes to hours 24-72 hours after exposure
Distribution Limited to contact area May spread beyond contact site
Patch testing May be positive for unrelated allergens Positive for specific allergens

Research indicates that ICD accounts for 80% of contact dermatitis cases, making it far more common than allergic reactions[1]. However, both conditions can coexist, particularly in occupational settings where multiple exposures occur.

Symptoms and Clinical Presentation of Irritant Dermatitis

The clinical appearance of irritant dermatitis varies depending on exposure duration, irritant strength, and individual factors. Understanding symptom patterns helps distinguish ICD from other skin conditions.

Acute Presentation

Acute irritant reactions appear rapidly after contact with a strong irritant. The symptoms are your skin's immediate alarm system going off:

  • Immediate symptoms: A sharp burning, stinging, or painful sensation right at the site of contact.
  • Visible changes: Within minutes to hours, you'll see erythema (bright redness) and edema (swelling). In more severe cases from potent chemicals, you may develop vesicles (small blisters) or even bullae (large blisters).
  • Clear Boundaries: The affected area often has a sharp, well-defined border that perfectly matches where the irritant touched the skin.

Chronic Presentation

Long-term, repeated exposure to milder irritants produces a different and more persistent set of symptoms[7]:

  • Skin changes: A constant feeling of dryness, visible scaling, and hyperkeratosis (a noticeable thickening of the skin as it tries to protect itself).
  • Texture alterations: The skin may develop a leathery, hardened appearance known as lichenification. Painful fissures (cracks) can appear, especially over knuckles and fingertips.
  • Color changes: Over time, the affected skin can develop hyperpigmentation (darkening) or hypopigmentation (lightening).
  • Persistent Symptoms: Instead of a sharp burn, the primary feelings are a constant, low-grade itch, tenderness to the touch, and reduced flexibility of the skin.

Research Finding: Studies using advanced imaging show that subclinical barrier damage occurs before visible symptoms, explaining why prevention is more effective than treatment[16].

Diagnosis and Testing for Irritant Dermatitis

Accurate diagnosis of irritant dermatitis requires a careful clinical evaluation and ruling out other conditions like psoriasis or different types of eczema. There is no single "test" for ICD; the diagnosis is primarily made through a detailed history and physical examination. The Mathias criteria, a checklist for occupational dermatitis, provide a systematic approach for dermatologists[17].

Clinical Assessment

A dermatologist will act like a detective to pinpoint the cause. The diagnosis typically involves connecting the dots between your exposures and your symptoms:

  1. Detailed Exposure History: What chemicals, substances, and materials does your skin contact daily at work and at home?
  2. Timeline Correlation: Do your symptoms appear or worsen after certain activities (e.g., after a work shift, after cleaning the house) and improve during time away (e.g., on weekends or vacation)?
  3. Physical Examination: The location and appearance of the rash provide crucial clues. A rash confined to the hands in a healthcare worker, for example, points strongly toward an occupational cause.
  4. Occupational Assessment: Reviewing workplace safety data sheets and understanding your specific job tasks.
  5. Grooming and shaving practices: Frequency and timing of shaving, technique (with or against hair growth), and products used (foams, gels, aftershaves) in relation to flare patterns.

Diagnostic Testing

While no specific test confirms ICD, several assessments are valuable for ruling out other conditions, especially allergic contact dermatitis:

  • Patch testing: This is the key test to identify allergic contact dermatitis. Small amounts of common allergens are applied to your back to see if an allergic reaction develops. A negative patch test makes irritant dermatitis more likely to be the primary cause[14].
  • Skin biopsy: A small sample of skin is examined under a microscope. While it can't definitively prove ICD, it helps rule out other conditions like psoriasis or fungal infections that can look similar.
  • pH measurement: Healthy skin is acidic (pH 4-6). A higher, more alkaline pH on the skin surface is a clear indicator of a damaged skin barrier.
  • Transepidermal water loss (TEWL): This non-invasive measurement uses a probe to quantify how much water is evaporating from your skin. High TEWL levels confirm that the skin barrier is "leaky" and damaged.

Clinical Pearl: In our experience, the single most useful diagnostic tool is the patient's history. A rash that consistently improves when away from work or a specific home environment is almost certainly an irritant dermatitis, even if patch tests are negative.

Treatment Approaches for Irritant Dermatitis

Finding the right treatment is about more than just calming the rash you have now; it's about creating a long-term strategy for healthy skin. Effective management requires a multi-pronged approach that addresses symptoms, repairs the skin barrier, and prevents future flares. Recent studies show these combination therapies achieve far better outcomes than single interventions[18].

⚠️ Important: Never use a potent topical steroid for more than two weeks without medical supervision, especially on the hands or face. While effective for initial relief, overuse can lead to skin thinning and other side effects.

Immediate Management

When your skin is actively inflamed, the first priority is to calm it down:

  1. Irritant identification and elimination: The most crucial step
  2. Gentle cleansing: Lukewarm water with mild, fragrance-free cleansers
  3. Barrier protection: Immediate application of occlusive agents

Topical Therapies

Evidence-based topical treatments include:

Barrier creams and potent emollients form the foundation of any effective treatment plan. Emollients are central to treatment, improving skin hydration and barrier function. A major review of studies concluded that emollients are a mainstay of hand eczema management.[19]

Topical Corticosteroids

Topical corticosteroids are first-line prescription treatments that reduce inflammation and alleviate itching. Studies show hydrocortisone 0.5-1% effectively manages mild ICD without causing skin thinning when used appropriately[19]. For sensitive areas or long-term use, a gentle yet effective formulation is key.

A Balanced Approach: Some newer formulations, like SmartLotion, combine a safe, low-dose hydrocortisone (0.75%) with prebiotics. This dual-action approach addresses both inflammation and supports a healthy skin microbiome, making it a suitable option for managing chronic irritant dermatitis safely over time.

Calcineurin inhibitors: Tacrolimus and pimecrolimus offer steroid-free alternatives, particularly useful for facial and intertriginous areas where steroids pose higher risks[19].

Barrier repair creams: Formulations containing ceramides, fatty acids, and cholesterol help restore barrier function. Clinical trials demonstrate up to 63% improvement in barrier integrity with consistent use[6].

2-4 weeks

Minimum time needed for barrier repair with proper treatment

Systemic Therapies

For severe, refractory cases, systemic treatments may be necessary. These are medications taken orally that work throughout the body, reserved for when topical treatments are not enough to control the dermatitis.

  • Alitretinoin: This is an oral retinoid (a form of Vitamin A) specifically approved for severe chronic hand eczema that hasn't responded to potent topical steroids. It can lead to complete or almost complete skin clearance in up to 43% of patients, offering hope for very difficult cases[19].
  • Other Systemic Agents: For the most severe situations, dermatologists may use powerful immune-suppressing drugs like cyclosporine, methotrexate, or azathioprine. Oral corticosteroids (like prednisone) may also be used for short periods to control severe flares[19].

Barrier Repair and Recovery in Irritant Dermatitis

So, how do you rebuild the wall? Understanding the science of your skin barrier is the key to true recovery. The outer layer of your skin, the stratum corneum, functions like a brick wall: skin cells (corneocytes) are the "bricks," and a complex mixture of lipids serves as the "mortar" holding everything together[19].

Components of Barrier Repair

Effective barrier restoration isn't just about moisture; it's about providing the exact building blocks your skin has lost:

  1. Lipid replacement: The mortar is made of ceramides, cholesterol, and fatty acids. Research shows that creams using these lipids in a 3:1:1 ratio are highly effective at repairing the barrier[21].
  2. pH normalization: Acidic formulations (pH 4-6) optimize enzyme function
  3. Hydration: Humectants draw water into epidermis
  4. Protection: Occlusives (like petrolatum) create a temporary seal over the skin to prevent transepidermal water loss (water evaporation) while the barrier heals underneath.

Research demonstrates that physiologic lipid replacement accelerates recovery. A study of healthcare workers showed nearly 60% improvement in transepidermal water loss after 4 weeks of ceramide-containing moisturizer use[19]. Your skin knows how to heal; your job is to give it the right tools.

Week 1-2: Acute Phase

Inflammation reduction, symptom relief with topical steroids

Week 2-4: Repair Phase

Barrier restoration with intensive moisturization

Week 4-8: Strengthening Phase

Continued barrier support, gradual activity resumption

Week 8+: Maintenance

Long-term protective measures and monitoring

The Role of the Microbiome

Emerging research reveals that irritant dermatitis disrupts the skin microbiome, creating conditions favorable for pathogenic bacteria. Maintaining microbial balance through pH-balanced cleansers and prebiotic ingredients supports healing[22].

Prevention Strategies

Prevention remains more effective than treatment for irritant dermatitis. Because the skin barrier can take weeks to fully recover, protecting it from re-injury is the most important part of long-term success. Comprehensive prevention programs can lead to symptom improvement in over 60% of patients[23].

Primary Prevention

The best strategy is to avoid irritant exposure in the first place. This involves making smart changes in your environment:

  • Substitution: Swap harsh chemicals for gentler alternatives. For example, use a pH-neutral soap instead of a harsh detergent.
  • Engineering controls: In a workplace, this could mean using automated systems that reduce direct skin contact with chemicals.
  • Administrative controls: At work, this involves rotating tasks to limit how long any one person is exposed to an irritant.

Personal Protective Equipment (PPE)

Proper glove use is crucial but more complex than it seems. Studies show that 90% of occupational dermatitis involves the hands[24], making gloves your first line of defense. But the wrong gloves, or wearing them improperly, can sometimes make things worse by trapping moisture and heat.

Key considerations for effective glove use include:

  • Choose the right material: Use nitrile or vinyl gloves for chemical irritants, as latex can cause allergies.
  • Use cotton liners: Wear thin cotton gloves inside your waterproof gloves to absorb sweat and reduce friction.
  • Keep them dry: Never wash and reuse disposable gloves. Always allow your hands to dry completely before putting on a new pair.
  • Check for holes: Even a tiny pinhole can trap irritants against your skin, causing significant damage.

Protective Skincare Regimen

A consistent skincare routine is a non-negotiable part of prevention. Think of it as building a stronger defense system for your skin, both before and after exposure.

A protective daily routine includes three key phases:

  1. Before Exposure (Pre-work): Apply a protective barrier cream or a gentle eczema cream before you start your day or handle irritants. This acts like an invisible shield.
  2. During Breaks (Maintenance): If you wash your hands frequently, reapply a quality moisturizer during breaks. Don't wait until your hands feel dry to reapply.
  3. After Exposure (Post-work/End of Day): Cleanse your skin with a gentle, lukewarm wash. Immediately follow up with an intensive moisturizer to replenish lost oils and hydration. For very dry hands, consider wearing cotton gloves over a thick layer of moisturizer overnight.

Shaving and Grooming Practices

Simple adjustments reduce shaving-related irritation:

  • Shave after a lukewarm shower when hair is hydrated
  • Use a sharp, clean blade and replace it regularly
  • Apply a pH-balanced, low-fragrance shaving gel or cream
  • Shave with hair growth using light pressure and minimal passes
  • Rinse with lukewarm water, then apply a barrier moisturizer immediately
  • Avoid alcohol-heavy aftershaves; choose soothing, non-stinging options
  • During active flares, consider an electric trimmer instead of a close wet shave

Occupational Considerations

Certain professions face a much higher risk for irritant dermatitis. Understanding the specific hazards of your job is the first step toward targeted prevention.

Healthcare Workers

Healthcare professionals experience the highest rates of occupational ICD, a problem that became significantly worse during the COVID-19 pandemic. Over 65% of healthcare staff reported hand dermatitis symptoms due to intensified hygiene protocols[24]. The main risk factors are a perfect storm for skin barrier breakdown:

  • Constant Hand Hygiene: Washing or sanitizing more than 20 times per shift strips the skin of its natural protective oils.
  • Harsh Sanitizers: High-concentration alcohol-based sanitizers are effective against germs but are extremely drying to the skin.
  • Glove Occlusion: Wearing gloves for hours traps sweat and heat, which can soften and weaken the skin barrier, a condition known as maceration.
  • Chemical Exposure: Regular contact with disinfectants and other cleaning agents adds another layer of irritation.

Hairdressers

With a lifetime prevalence of 38.2%, hairdressers are in a constant battle with skin irritants[6]. Their hands are exposed to a wide array of potent chemicals and constant moisture.

  • Wet work (shampooing)
  • Hair dyes and bleaches (persulfates are strong irritants)
  • Permanent wave solutions (alkaline chemicals)
  • Styling products containing alcohols and fragrances

Food Handlers

Restaurant workers, chefs, and food processors face a unique combination of wet work and natural irritants. Their hands are frequently exposed to:

  • Frequent hand washing
  • Food acids and juices
  • Cleaning chemicals
  • Temperature extremes
Occupation-Specific Prevention Strategies
Occupation Primary Hazards Prevention Focus
Healthcare Sanitizers, gloves Moisturize between hand hygiene
Hairdressing Chemicals, wet work Protective gloves, barrier creams
Food service Detergents, foods Task rotation, protective equipment
Cleaning Strong chemicals Proper dilution, ventilation

When to See a Dermatologist

While mild irritant dermatitis often responds to self-care, certain situations require professional evaluation to prevent complications.

When is Irritant Dermatitis Serious?

You should seek immediate medical attention if you experience any of the following red flags:

  • Severe reactions: Extensive blistering, chemical burns, or open, weeping wounds.
  • Signs of infection: Increased pain, warmth, pus drainage, or red streaks spreading from the rash.
  • Systemic symptoms: Developing a fever or noticing swollen lymph nodes.
  • Eye involvement: Any irritant exposure that affects the eyes or eyelids requires urgent care.

Indications for Specialist Referral

Consider dermatology consultation when:

  • Symptoms persist beyond 4 weeks despite treatment
  • Dermatitis interferes with work or daily activities, which can be covered as eczema is a disability if it limits your ability to work.
  • Diagnosis remains unclear after initial evaluation
  • Patch testing needed to exclude allergic components
  • Systemic therapy consideration

Questions for Your Dermatologist

  1. Could this be allergic rather than irritant dermatitis?
  2. Should I undergo patch testing?
  3. Are there occupational accommodations I should request?
  4. What's my prognosis for complete recovery?
  5. Are there newer treatments like biologics that might help?

Living with Irritant Dermatitis

Managing irritant dermatitis is a journey of understanding, patience, and consistent care. While the condition can significantly impact your quality of life, the evidence is clear: proper treatment combined with smart prevention leads to successful, long-term relief for the vast majority of people[26].

Your path forward is about identifying your personal triggers and committing to a routine that actively supports your skin's barrier. This means choosing products designed for sensitive, compromised skin and protecting your skin even when it feels healthy. This is how you break the cycle of irritation for good.

For those seeking gentle yet effective treatment options, newer formulations that combine anti-inflammatory ingredients with barrier support show promise. Products like eczema cream designed specifically for sensitive skin can provide relief without the risks associated with high-potency steroids.

Final Thought: Irritant dermatitis is not a failure of your skin or your care routine. It's a common response to environmental challenges that, with proper understanding and management, can be effectively controlled.

References

  1. Japundžić I, et al. Skin features important for the occurrence of contact dermatitis in healthcare workers. Acta Clinica Croatica, vol. 61, no. 4, 2023, pp. 692-702. View Study
  2. Veronese F, et al. Prevalence of Self-Reported Hand Eczema Signs among Healthcare Workers after the Third Wave of COVID-19 Pandemic: A Survey in a Northern Italy Hospital. Medicina (Kaunas), vol. 59, no. 6, 2023. View Study
  3. Loi AST, Aribou ZM, Fong YT. Improving Recovery of Irritant Hand Dermatitis in Healthcare Workers With Workplace Interventions During the COVID-19 Pandemic. Frontiers in Public Health, vol. 10, 2022, p. 844269. View Study
  4. Japundžić I, et al. Psychological Stress and Hand Eczema in Physicians and Dentists: A Comparison Based on Surgical Work. Behavioral Sciences, vol. 13, no. 5, 2023, p. 379. View Study
  5. Larese Filon F, et al. Incidence of occupational contact dermatitis in healthcare workers: a systematic review. Journal of the European Academy of Dermatology and Venereology, vol. 35, no. 6, 2021, pp. 1285-1289. View Study
  6. Larese Filon F, et al. Effectiveness of a Skin Care Program With a Cream Containing Ceramide C and a Personalized Training for Secondary Prevention of Hand Contact Dermatitis. Dermatitis, vol. 34, no. 2, 2023, pp. 127-134. View Study
  7. Novak-Bilić G, et al. Irritant and Allergic Contact Dermatitis - Skin Lesion Characteristics. Acta Clinica Croatica, vol. 57, no. 4, 2018, pp. 713-720. View Study
  8. Proksch E. pH in nature, humans and skin. Journal of Dermatology, vol. 45, no. 9, 2018, pp. 1044-1052. View Study
  9. Fan W, et al. Clinical Manifestations, Treatment, and Prevention of Acute Irritant Contact Dermatitis Caused by 2,4-Dichloro-5-Methylpyrimidine. Dermatitis, vol. 32, no. 1, 2021, pp. 63-67. View Study
  10. Behroozy A, Keegel TG. Wet-work exposure: a main risk factor for occupational hand dermatitis. Safety and Health at Work, vol. 5, no. 4, 2014, pp. 175-180. View Study
  11. Seité S, et al. Survey of Hand Issues Encountered by Hairdressers and Hairdresser Related Professionals: From Epidemiological Data to Clinical Observational Survey Results. Clinical, Cosmetic and Investigational Dermatology, vol. 16, 2023, pp. 111-117. View Study
  12. Agarwal US, et al. Hand eczema. Indian Journal of Dermatology, vol. 59, no. 3, 2014, pp. 213-24. View Study
  13. Loh EDW, Yew YW. Hand hygiene and hand eczema: A systematic review and meta-analysis. Contact Dermatitis, vol. 87, no. 4, 2022, pp. 303-314. View Study
  14. Loman L, et al. European Surveillance System on Contact Allergies (ESSCA): Characteristics of patients patch tested and diagnosed with irritant contact dermatitis. Contact Dermatitis, vol. 85, no. 2, 2021, pp. 186-197. View Study
  15. Karagounis TK, Cohen DE. Occupational Hand Dermatitis. Current Allergy and Asthma Reports, vol. 23, no. 4, 2023, pp. 201-212. View Study
  16. Lee HY, et al. Cytokines and chemokines in irritant contact dermatitis. Mediators of Inflammation, vol. 2013, 2013, p. 916497. View Study
  17. Yuindartanto A, et al. Occupational Contact Dermatitis Risk Factors on Healthcare Workers Isolation Ward During the COVID-19 Pandemic. Berkala Ilmu Kesehatan Kulit dan Kelamin, vol. 35, no. 1, 2023, pp. 27-39. View Study
  18. de León FJ, et al. Management of Chronic Hand Eczema. Actas Dermo-Sifiliográficas, vol. 106, no. 7, 2015, pp. 533-544. View Study
  19. Christoffers WA, et al. Interventions for hand eczema. Cochrane Database of Systematic Reviews, no. 4, 2019, p. CD004055. View Study
  20. Lund T, et al. Risk of work-related hand eczema in relation to wet work exposure. Scandinavian Journal of Work, Environment & Health, vol. 46, no. 4, 2020, pp. 437-445. View Study
  21. Kircik LH, et al. Evaluating Clinical Use of a Ceramide-dominant, Physiologic Lipid-based Topical Emulsion for Atopic Dermatitis. The Journal of Clinical and Aesthetic Dermatology, vol. 4, no. 3, 2011, pp. 34-40. View Study
  22. Ibler KS, et al. The Hand Eczema Trial (HET): design of a randomised clinical trial of the effect of classification and individual counselling versus no intervention among health-care workers with hand eczema. BMC Dermatology, vol. 10, 2010, p. 8. View Study
  23. Ibler KS, et al. Skin care education and individual counselling versus treatment as usual in healthcare workers with hand eczema: randomised clinical trial. BMJ, vol. 345, 2012, p. e7822. View Study
  24. Roy S, et al. Hand hygiene products and adverse skin reactions: A cross-sectional comparison between healthcare and non-healthcare workers of Bangladesh during COVID-19 pandemic. Heliyon, vol. 8, no. 12, 2022, p. e12295. View Study
  25. Ahmed ZH, et al. Hand Dermatitis: A Comprehensive Review with Special Emphasis on COVID-19 Pandemic. Indian Journal of Dermatology, vol. 66, no. 5, 2021, pp. 508-519. View Study
  26. Martin SF, et al. Recent advances in understanding and managing contact dermatitis. F1000Research, vol. 7, 2018, p. 810. View Study

About the Author: Michael Anderson, Clinical Research Project Manager

Michael bridges the gap between research labs and real patients. As our research project manager, he ensures groundbreaking studies translate into accessible treatments. A craft beer enthusiast and woodworking hobbyist, Michael approaches both his hobbies and research with the same attention to detail, although he admits that research protocols are significantly less forgiving than furniture joints.